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variants

Annotating Genomic Variants

Bioconductor version: 3.23 · Package version: 1.36.0

Read and write VCF files. Identify structural location of variants and compute amino acid coding changes for non-synonymous variants. Use SIFT and PolyPhen database packages to predict consequence of amino acid coding changes.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("variants")

Details

MaintainerBioconductor Package Maintainer <maintainer@bioconductor.org>
AuthorValerie Obenchain [aut], Martin Morgan [ctb], Bioconductor Package Maintainer [cre]
LicenseArtistic-2.0
URLhttps://bioconductor.org/help/workflows/variants/
Downloads rank143
Source branchRELEASE_3_23
biocViewsAnnotationWorkflow, ImmunoOncologyWorkflow, Workflow

Download

Follow the installation instructions to use this package in your R session.

Source packagevariants_1.36.0.tar.gz
Dependencies

Depends: R (>= 3.3.0), GenomeInfoDb, VariantAnnotation, org.Hs.eg.db, TxDb.Hsapiens.UCSC.hg19.knownGene, BSgenome.Hsapiens.UCSC.hg19, PolyPhen.Hsapiens.dbSNP131

Suggests: knitr, rmarkdown, BiocStyle