trio
Testing of SNPs and SNP Interactions in Case-Parent Trio Studies
Bioconductor version: 3.23 · Package version: 3.50.0
Testing SNPs and SNP interactions with a genotypic TDT. This package furthermore contains functions for computing pairwise values of LD measures and for identifying LD blocks, as well as functions for setting up matched case pseudo-control genotype data for case-parent trios in order to run trio logic regression, for imputing missing genotypes in trios, for simulating case-parent trios with disease risk dependent on SNP interaction, and for power and sample size calculation in trio data.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("trio") Details
| Maintainer | Holger Schwender <holger.schw@gmx.de> |
| Author | Holger Schwender, Qing Li, Philipp Berger, Christoph Neumann, Margaret Taub, Ingo Ruczinski |
| License | LGPL-2 |
| Downloads rank | 566 |
| Source branch | RELEASE_3_23 |
| biocViews | GeneticVariability, Genetics, Microarray, SNP, Software |
Documentation
Download
Follow the installation instructions to use this package in your R session.
| Source package | trio_3.50.0.tar.gz |
| Windows binary (x86_64) | trio_3.50.0.zip |
| macOS binary (arm64) | trio_3.50.0.tgz |
| macOS binary (x86_64) | trio_3.50.0.tgz |
Dependencies
Depends: R (>= 3.0.1)
Imports: grDevices, graphics, methods, stats, survival, utils, siggenes, LogicReg (>= 1.6.1), data.table
Suggests: mcbiopi, splines, logicFS (>= 1.28.1), KernSmooth, VariantAnnotation