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metapone

Conducts pathway test of metabolomics data using a weighted permutation test

Bioconductor version: 3.23 · Package version: 1.18.0

The package conducts pathway testing from untargetted metabolomics data. It requires the user to supply feature-level test results, from case-control testing, regression, or other suitable feature-level tests for the study design. Weights are given to metabolic features based on how many metabolites they could potentially match to. The package can combine positive and negative mode results in pathway tests.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("metapone")

Details

MaintainerTianwei Yu <yutianwei@cuhk.edu.cn>
AuthorLeqi Tian [aut], Tianwei Yu [aut], Tianwei Yu [cre]
LicenseArtistic-2.0
Downloads rank414
Source branchRELEASE_3_23
biocViewsMassSpectrometry, Metabolomics, Pathways, Software, Technology

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagemetapone_1.18.0.tar.gz
Windows binary (x86_64)metapone_1.18.0.zip
macOS binary (arm64)metapone_1.18.0.tgz
macOS binary (x86_64)metapone_1.18.0.tgz
Dependencies

Depends: R (>= 4.1.0), BiocParallel, fields, markdown, fdrtool, fgsea, ggplot2, ggrepel

Imports: methods

Suggests: rmarkdown, knitr