gscreend
Analysis of pooled genetic screens
Bioconductor version: 3.23 · Package version: 1.26.0
Package for the analysis of pooled genetic screens (e.g. CRISPR-KO). The analysis of such screens is based on the comparison of gRNA abundances before and after a cell proliferation phase. The gscreend packages takes gRNA counts as input and allows detection of genes whose knockout decreases or increases cell proliferation.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("gscreend")Details
| Maintainer | Katharina Imkeller <k.imkeller@dkfz.de> |
| Author | Katharina Imkeller [cre, aut], Wolfgang Huber [aut] |
| License | GPL-3 |
| URL | https://github.com/imkeller/gscreend |
| Bug Reports | https://github.com/imkeller/gscreend/issues |
| Downloads rank | 430 |
| Source branch | RELEASE_3_23 |
| biocViews | CRISPR, PooledScreens, Software, StatisticalMethod |
Documentation
Download
Follow the installation instructions to use this package in your R session.
| Source package | gscreend_1.26.0.tar.gz |
| Windows binary (x86_64) | gscreend_1.26.0.zip |
| macOS binary (arm64) | gscreend_1.26.0.tgz |
| macOS binary (x86_64) | gscreend_1.26.0.tgz |
Dependencies
Depends: R (>= 3.6)
Imports: SummarizedExperiment, nloptr, fGarch, methods, BiocParallel, graphics