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HMMcopy

Copy number prediction with correction for GC and mappability bias for HTS data

Bioconductor version: 3.23 · Package version: 1.54.0

Corrects GC and mappability biases for readcounts (i.e. coverage) in non-overlapping windows of fixed length for single whole genome samples, yielding a rough estimate of copy number for furthur analysis. Designed for rapid correction of high coverage whole genome tumour and normal samples.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("HMMcopy")

Details

MaintainerDaniel Lai <dalai@bccrc.ca>
AuthorDaniel Lai, Gavin Ha, Sohrab Shah
LicenseGPL-3
Downloads rank768
Source branchRELEASE_3_23
biocViewsCopyNumberVariation, Microarray, Preprocessing, Sequencing, Software, Visualization

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageHMMcopy_1.54.0.tar.gz
Windows binary (x86_64)HMMcopy_1.54.0.zip
macOS binary (arm64)HMMcopy_1.54.0.tgz
macOS binary (x86_64)HMMcopy_1.54.0.tgz
Dependencies

Depends: R (>= 2.10.0), data.table (>= 1.11.8)

Reverse dependencies

Imports Me (1): qsea