CNAnorm
A normalization method for Copy Number Aberration in cancer samples
Bioconductor version: 3.23 · Package version: 1.58.0
Performs ratio, GC content correction and normalization of data obtained using low coverage (one read every 100-10,000 bp) high troughput sequencing. It performs a "discrete" normalization looking for the ploidy of the genome. It will also provide tumour content if at least two ploidy states can be found.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("CNAnorm")Details
| Maintainer | Stefano Berri <sberri@illumina.com> |
| Author | Stefano Berri <sberri@illumina.com>, Henry M. Wood <H.M.Wood@leeds.ac.uk>, Arief Gusnanto <a.gusnanto@leeds.ac.uk> |
| License | GPL-2 |
| URL | http://www.r-project.org, |
| Downloads rank | 471 |
| Source branch | RELEASE_3_23 |
| biocViews | CopyNumberVariation, Coverage, DNASeq, GenomicVariation, Normalization, Sequencing, Software, WholeGenome |
Documentation
Download
Follow the installation instructions to use this package in your R session.
| Source package | CNAnorm_1.58.0.tar.gz |
| Windows binary (x86_64) | CNAnorm_1.58.0.zip |
| macOS binary (arm64) | CNAnorm_1.58.0.tgz |
| macOS binary (x86_64) | CNAnorm_1.58.0.tgz |