Package: SpaNorm
Title: Spatially-aware normalisation for spatial transcriptomics data
Version: 1.4.0
Authors@R: c(
            person(given = "Dharmesh D.",
                   family = "Bhuva",
                   role = c("aut", "cre"),
                   email = "dharmesh.bhuva@adelaide.edu.au",
                   comment = c(ORCID = "0000-0002-6398-9157")),
            person(given = "Agus",
                   family = "Salim",
                   role = c("aut"),
                   email = "salim.a@unimelb.edu.au",
                   comment = c(ORCID = "0000-0003-3999-7701")),
            person(given = "Ahmed",
                   family = "Mohamed",
                   role = c("aut"),
                   email = "mohamed.a@wehi.edu.au",
                   comment = c(ORCID = "0000-0001-6507-5300"))
            )
Description: This package implements the spatially aware library size
        normalisation algorithm, SpaNorm. SpaNorm normalises out
        library size effects while retaining biology through the
        modelling of smooth functions for each effect. Normalisation is
        performed in a gene- and cell-/spot- specific manner, yielding
        library size adjusted data.
License: GPL (>= 3)
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
biocViews: Software, GeneExpression, Transcriptomics, Spatial,
        CellBiology
Depends: R (>= 4.4)
Imports: edgeR, ggplot2, Matrix, matrixStats, methods, rlang, scran,
        SeuratObject, SingleCellExperiment, SpatialExperiment, stats,
        SummarizedExperiment, S4Vectors, utils
Suggests: testthat (>= 3.0.0), knitr, rmarkdown, prettydoc, pkgdown,
        covr, BiocStyle, Seurat, patchwork, ggforce, ggnewscale
URL: https://bhuvad.github.io/SpaNorm
BugReports: https://github.com/bhuvad/SpaNorm/issues
VignetteBuilder: knitr
Config/testthat/edition: 3
LazyData: false
Config/pak/sysreqs: libglpk-dev libmagick++-dev gsfonts libicu-dev
        libxml2-dev libssl-dev
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2025-10-29 15:32:47 UTC
RemoteUrl: https://github.com/bioc/SpaNorm
RemoteRef: RELEASE_3_22
RemoteSha: 3627d0d79e8fe58885854bd7ac9b94922eaff84e
NeedsCompilation: no
Packaged: 2025-11-11 17:48:26 UTC; root
Author: Dharmesh D. Bhuva [aut, cre] (ORCID:
    <https://orcid.org/0000-0002-6398-9157>),
  Agus Salim [aut] (ORCID: <https://orcid.org/0000-0003-3999-7701>),
  Ahmed Mohamed [aut] (ORCID: <https://orcid.org/0000-0001-6507-5300>)
Maintainer: Dharmesh D. Bhuva <dharmesh.bhuva@adelaide.edu.au>
Built: R 4.5.2; ; 2025-11-11 17:58:53 UTC; windows
