.AdjustColumnName | Adjust Column Names of Input Data Table |
.Bootstrapping | Bootstraping Sample from Replicates in Response Data |
.Distance | Calculate Distance from a Point to a Plane |
.ExtendedScores | Make a Smooth Surface for Scores |
.Extract2DrugPlotData | Extract Data for 2 Drug Combination Plots |
.ExtractMultiDrugPlotData | Extract Data Table and Annotation Information for Multi-drug Plotting |
.Own_log | CSS Facilitate Function - Log Calculation (nature based) LL.4 Model |
.Own_log2 | CSS Facilitate Function - Log (nature based) Calculation L.4 Model |
.PredictResponseFromModel | Predict Response Value at Certain Drug Dose |
.Pt2mm | Convert Font Size from pt to mm |
.RoundValues | Round the Numbers for Plotting |
.ScoreCurve | CSS Facilitate Function - .ScoreCurve for Curves Fitted by LL.4 Model |
.ScoreCurve_L4 | CSS Facilitate Function - .ScoreCurve for Curves Fitted by L.4 Model |
.SolveExpDoesL4 | Solve the Expected Dose of Drug to Achieve Given Effect from L.4 Model |
.SolveExpDoesLL4 | Solve the Expected Dose of Drug to Achieve Given Effect from LL.4 Model |
.SolveExpDose | Solve the Expected Dose of Drug to Achieve Given Effect (% inhibition) |
.SolveLoewe | Solve the Loewe Additive Effect for Concentration Combinations Isobologram |
Bliss | Calculate Bliss Synergy Score |
CalculateCSS | Calculate Combination Sensitivity Score |
CalculateIC50 | Calculate Relative IC50 from Fitted Model |
CalculateRI | Calculate Relative Inhibition (RI) for Dose-Response Curve |
CalculateSensitivity | Calculate the Sensitivity Scores for Drug Combinations |
CalculateSynergy | Calculate the Synergy Scores for Drug Combinations |
CorrectBaseLine | Base Line Correction for Drug Combination Matrix |
DimensionReduction | Dimension Reduction for Multi-drug Combination Visualization |
ExtractSingleDrug | Extract Single Drug Dose Response |
FindModelPar | Find the Fitted Parameters from 4-Parameter Log-Logistic Model |
FindModelType | Find the Type of Model Used for Fitting Dose Response Data |
FitDoseResponse | Fitting Single Drug Dose-Response Model |
GenerateSurface | 3D Surface Plot for Nulti-drug Combination Dose-Response/Synergy Scores |
HighlightBarPlot | Highlight Bars |
HSA | Calculate HSA Synergy Score |
ImputeIC50 | Impute Missing Value at IC50 Concentration of Drug |
Loewe | Calculate Loewe Synergy Score |
mathews_screening_data | A high-throughput drug combination screening data |
NCATS_screening_data | A high-throughput 3 drug combination screening data |
ONEIL_screening_data | A high-throughput 2 drugs combination screening data with replication |
Plot2DrugContour | 2D Contour Plot for 2-drug Combination Dose-Response/Synergy Scores |
Plot2DrugHeatmap | Heatmap Plot for 2-drug Combination Dose-Response/Synergy Scores |
Plot2DrugSurface | 3D Surface Plot for 2-drug Combination Dose-Response/Synergy Scores |
PlotBarometer | Plot Barometer for Responses at One Data Point |
PlotDoseResponse | Visualize the Drug Combination Dose-response Data |
PlotDoseResponseCurve | Plot Dose Response Curve for Single Drug |
PlotMultiDrugBar | Bar Plot for Multi-drug Combination Dose-Response/Synergy Scores |
PlotMultiDrugSurface | 3D Plot for Multi-drug Combination Dose-Response/Synergy Scores |
PlotSensitivitySynergy | Plot Sensitive-Synergy Plot for All the Combinations in the Input Data |
PlotSynergy | Plot Interaction Landscape for Synergy Scores |
PredictResponse | Predict Response Value at Certain Drug Dose |
ReshapeData | Pre-process the Response Data for Further Calculation and Plot |
ZIP | Calculate Delta Synergy Score Based on ZIP Model |