 
  
 
   
   This package is for version 3.15 of Bioconductor; for the stable, up-to-date release version, see DominoEffect.
Bioconductor version: 3.15
The functions support identification and annotation of hotspot residues in proteins. These are individual amino acids that accumulate mutations at a much higher rate than their surrounding regions.
Author: Marija Buljan and Peter Blattmann
Maintainer: Marija Buljan <marija.buljan.2 at gmail.com>, Peter Blattmann <blattmann at imsb.biol.ethz.ch>
Citation (from within R,
      enter citation("DominoEffect")):
To install this package, start R (version "4.2") and enter:
if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")
BiocManager::install("DominoEffect")
    For older versions of R, please refer to the appropriate Bioconductor release.
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("DominoEffect")
    
| HTML | R Script | Vignette for DominoEffect package | 
| Reference Manual | ||
| Text | NEWS | 
| biocViews | Alignment, Proteomics, SequenceMatching, Software, SomaticMutation | 
| Version | 1.16.0 | 
| In Bioconductor since | BioC 3.7 (R-3.5) (4.5 years) | 
| License | GPL (>= 3) | 
| Depends | R (>= 3.5) | 
| Imports | biomaRt, data.table, utils, stats, Biostrings, SummarizedExperiment, VariantAnnotation, AnnotationDbi, GenomeInfoDb, IRanges, GenomicRanges, methods | 
| LinkingTo | |
| Suggests | knitr, testthat, rmarkdown | 
| SystemRequirements | |
| Enhances | |
| URL | |
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Links To Me | |
| Build Report | 
Follow Installation instructions to use this package in your R session.
| Source Package | DominoEffect_1.16.0.tar.gz | 
| Windows Binary | DominoEffect_1.16.0.zip (64-bit only) | 
| macOS Binary (x86_64) | DominoEffect_1.16.0.tgz | 
| Source Repository | git clone https://git.bioconductor.org/packages/DominoEffect | 
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/DominoEffect | 
| Package Short Url | https://bioconductor.org/packages/DominoEffect/ | 
| Package Downloads Report | Download Stats | 
 
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