noob {sesame}R Documentation

Noob background correction

Description

The function takes a SigSet and returns a modified SigSet with background subtracted. Background was modelled in a normal distribution and true signal in an exponential distribution. The Norm-Exp deconvolution is parameterized using Out-Of-Band (oob) probes

Usage

noob(sset, bgR = NULL, bgG = NULL, offset = 15)

Arguments

sset

a SigSet

bgR

background red probes, if not given use all oobR

bgG

background grn probes, if not given use all oobG

offset

offset

Value

a new SigSet with noob background correction

Examples

sset <- makeExampleTinyEPICDataSet()
sset.nb <- noob(sset)

[Package sesame version 1.10.5 Index]