avaSetFiltered_annot {R453Plus1Toolbox} | R Documentation |
These are example annotations for 4 variants of an AVASet (try data(avaSetFiltered)
to retrieve the corresponding link{AVASet-class}
object).
The annotations include affected genes, exons and codons as well as resulting amino acid changes and dbSNP identifiers (if the mutation is already known).
data(avaSetFiltered_annot)
Formal class 'AnnotatedVariants'
‘Next-generation sequencing technology reveals a characteristic pattern of molecular mutations in 72.8% of chronic myelomonocytic leukemia by detecting frequent alterations in TET2, CBL, RAS, and RUNX1’ (Kohlmann A et al., J Clin Oncol. 2010 Aug 20;28(24):3858-65. Epub 2010 Jul 19)
data(avaSetFiltered_annot)