get_prior_Gerstein {KBoost}R Documentation

Function to build a prior using a previously built Network on ChIP-Seq.

Description

Function to build a prior using a previously built Network on ChIP-Seq.

Usage

get_prior_Gerstein(gen_names, TFs, pos_weight, neg_weight)

Arguments

gen_names

the gene names in Symbol nomenclature.

TFs

the indexes of gene names which are TFs.

pos_weight

the prior weight for edges previously found in Gerstein 2011

neg_weight

the prior weight for edges not found in the Gerstein 2011/

Value

matrix with prior probabilities of the Tf target edges.

Examples

gen_names = c("TP53","MDM2","FOXM1","ESR1","CTCF","YY1")
tfs = get_tfs_human(gen_names)
prior = get_prior_Gerstein(gen_names,tfs,0.6,0.4)


[Package KBoost version 1.0.0 Index]