directionalityIndex {HiTC}R Documentation

Directionality index calculation

Description

Calculate the directionality index as proposed by Dixon et al. 2012

Usage

directionalityIndex(x, winup = 2e+06, windown = 2e+06)

Arguments

x

HTClist object

winup

size of upstream window

windown

size of downstrean window

Details

Calculate the directionality index as proposed by Dixon et al. This index is then used to call topological domains in Hi-C/5C data.

Value

A numeric vector

Author(s)

N. Servant

See Also

HTClist-class

Examples

require(HiCDataHumanIMR90)
data(Dixon2012_IMR90)
hox <- extractRegion(hic_imr90_40$chr6chr6, chr="chr6", from=50e6, to=58e6)
di<-directionalityIndex(hox)

[Package HiTC version 1.36.0 Index]