HGNC gene symbols in rows, pathways in columns. Pathway activity inference works by matrix multiplication of gene expression with the model.

Format

The full human model contains 22479 genes, associated pathways, weight and the p-value.

gene

gene names in HGNC symbols

pathway

names of PROGENy pathways

weight

z-scores for a given gene

p.value

significance of gene in pathway

Source

https://www.nature.com/articles/s41467-017-02391-6

Examples

get("model_human_full", envir = .GlobalEnv)