test.posterior {CNVtools}R Documentation

Checks posterior probabilities are monotonic.

Description

The posterior probability of belonging to a particular component should fall to zero monotonically as the signal increases or decreases away from the component mean. This function checks for posterior distributions that do not have this property.

Usage

test.posterior(frame, ncomp, samples.by.disease = NULL)

Arguments

frame

Posterior data frame.

ncomp

Number of components.

samples.by.disease

List containing samples split on disease status.

Value

Returns TRUE is the posterior is not monotonic.

Author(s)

Vincent Plagnol vincent.plagnol@cimr.cam.ac.uk and Chris Barnes christopher.barnes@imperial.ac.uk


[Package CNVtools version 1.81.0 Index]