pwrEWAS_deltaDensity {pwrEWAS} | R Documentation |
pwrEWAS_deltaDensity create a density plot of the simulated differences in mean methylation for different effect sizes
pwrEWAS_deltaDensity(data, detectionLimit = 0.01, sd = FALSE)
data |
"deltaArray" attribute within the pwrEWAS object create by pwrEWAS |
detectionLimit |
Detection limit specified in pwrEWAS. |
sd |
FALSE if targetDelta was specified in pwrEWAS, and TRUE if deltaSD was specified in pwrEWAS. |
pwrEWAS_deltaDensity return a figure displaying densities of simulated differences in mean methylation different effect sizes
outDelta <- pwrEWAS(minTotSampleSize = 10, maxTotSampleSize = 20, SampleSizeSteps = 10, NcntPer = 0.5, targetDelta = c(0.2, 0.5), J = 1000, targetDmCpGs = 10, tissueType = "Adult (PBMC)", detectionLimit = 0.01, DMmethod = "limma", FDRcritVal = 0.05, core = 2, sims = 30) pwrEWAS_deltaDensity(data = outDelta$deltaArray, detectionLimit = 0.01, sd = FALSE) outSD <- pwrEWAS(minTotSampleSize = 10, maxTotSampleSize = 20, SampleSizeSteps = 10, NcntPer = 0.5, deltaSD = c(0.02, 0.03), J = 1000, targetDmCpGs = 10, tissueType = "Adult (PBMC)", detectionLimit = 0.01, DMmethod = "limma", FDRcritVal = 0.05, core = 2, sims = 30) pwrEWAS_deltaDensity(data = outSD$deltaArray, detectionLimit = 0.01, sd = TRUE)