Calculate and Visualize Synergy Scores for Drug Combinations


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Documentation for package ‘synergyfinder’ version 2.0.12

Help Pages

.ExtendedScores Make a smooth surface for scores
AddNoise Add noise to response value
Bliss Calculate Bliss synergy score
CalculateSynergy Calculate the synergy scores for drug combinations
CorrectBaseLine Base line correction
ExtractSingleDrug Extract single drug response from matrix
FindModelType Find the type of model used for fitting dose response data
FitDoseResponse Fitting single drug dose-response model
HSA Calculate HSA synergy score
ImputeNA Impute missing value with nearest values
kriging Kriging
Loewe Calculate Loewe synergy score
mathews_screening_data A high-throughput drug combination screening data
PlotDoseResponse Visualize the drug combination dose-response data
PlotSynergy Drug interaction landscape
ReshapeData Pre-processe the response data for furhter calculation and plot
ZIP Calculate Delta synergy score based on ZIP model