TPP-package | Thermal proteome profiling (TPP) |
.onLoad | Thermal proteome profiling (TPP) |
analyzeTPPCCR | Analyze TPP-CCR experiment |
analyzeTPPTR | Analyze TPP-TR experiment |
hdacCCR_config_repl1 | The configuration table to analyze hdacCCR_data_repl1. |
hdacCCR_config_repl2 | The configuration table to analyze hdacCCR_data_repl2. |
hdacCCR_data_repl1 | TPP-CCR example dataset (replicate 1) |
hdacCCR_data_repl2 | TPP-CCR example dataset (replicate 2) |
hdacCCR_smallExample | Example subsets of a Panobinostat TPP-CCR dataset (replicates 1 and 2) and the corresponding configuration tables to start the analysis. |
hdacTR_config | The configuration table to analyze hdacTR_data. |
hdacTR_data | TPP-TR example dataset. |
hdacTR_fittedData_smallExample | Example of a TPP-TR dataset with fitted melting curve parameters. |
hdacTR_resultsTable_smallExample | Example of a TPP-TR result table. |
hdacTR_smallExample | Example subset of a Panobinostat TPP-TR dataset and the corresponding configuration table to start the analysis. |
resultTable | Example of a TPP-TR result table. |
TPP | Thermal proteome profiling (TPP) |
tppccrCurveFit | Fit and analyse dose response curves |
tppccrImport | Import TPP-CCR dataset for analysis by the 'TPP' package. |
tppccrNormalize | Normalize data from TPP-CCR experiments |
tppccrTransform | Transform fold changes of TPP-CCR experiment |
tppDefaultTheme | Default ggplot theme for melting curve plots. |
tppExport | Produce Excel table of TPP-TR or TPP-CCR experiment. |
tppQCPlotsCorrelateExperiments | Plot pairwise relationships between the proteins in different TPP experiments. |
tpptrCurveFit | Fit melting curves to all proteins in a dataset. |
tpptrDefaultNormReqs | Default filter criteria for fold change normalization |
tpptrImport | Import TPP-TR datasets for analysis by the 'TPP' package. |
tpptrNormalize | Normalize protein fold changes |
tpptrQCPlotsMinSlopes_vs_MPdiffs | Plot minSlope vs. melting point differences |
tpptrResultTable | Statistical analysis of melting curve parameters. |
tppVenn | Venn diagrams of detected proteins per experiment. |
trDataFitted | Example of a TPP-TR dataset with fitted melting curve parameters. |