source("http://bioconductor.org/biocLite.R")
biocLite("DSS")

DSS

Dispersion shrinakge for sequencing data.

Bioconductor version: 2.13

DSS is an R library performing differntial analysis for count-based sequencing data. It detectes differentially expressed genes (DEGs) from RNA-seq, and differentially methylated loci or regions (DML/DMRs) from bisulfite sequencing (BS-seq). The core of DSS is a new dispersion shrinkage method for estimating the dispersion parameter from Gamma-Poisson or Beta-Binomial distributions.

Author: Hao Wu <hao.wu at emory.edu>

Maintainer: Hao Wu <hao.wu at emory.edu>

Installation

To install this package, start R and enter:

source("http://bioconductor.org/biocLite.R")
biocLite("DSS")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DSS")

 

PDF	R Script	Differential expression for RNA-seq data with dispersion shrinkage
PDF		Reference Manual
Text		NEWS

Details

biocViews	ChIPseq, DNAMethylation, DifferentialExpression, HighThroughputSequencing, RNAseq, Software
Version	1.8.0
In Bioconductor since	BioC 2.11 (R-2.15)
License	GPL
Depends	Biobase, locfdr
Imports	methods, bsseq, edgeR
Suggests
System Requirements
URL
Depends On Me
Imports Me
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Package Archives

Follow Installation instructions to use this package in your R session.

Package Source	DSS_1.8.0.tar.gz
Windows Binary	DSS_1.8.0.zip (32- & 64-bit)
Mac OS X 10.6 (Snow Leopard)	DSS_1.8.0.tgz
Browse/checkout source	(username/password: readonly)
Package Downloads Report	Download Stats